About
Dr. Natalie Gentile is a Pittsburgh native from Mt. Lebanon with board certifications in both Family Medicine and Lifestyle Medicine. She graduated from St. Vincent College with a Bachelor of Science in Biology before earning her medical degree from the University of Pittsburgh School of Medicine in 2014. She completed her Family Medicine residency at Mayo Clinic in 2017, then joined Mayo's Department of Family Medicine in Rochester, Minnesota as an attending physician through 2019.
Her experience at Mayo Clinic deepened her commitment to addressing root causes of disease rather than managing symptoms alone. She co-founded Direct Care Physicians of Pittsburgh with Dr. Kirsten Lin and opened Gentile Family Direct Primary Care in 2019. In 2023 she opened Rebel Wellness in Pittsburgh's East End, a lifestyle medicine-oriented space offering teaching kitchen classes, personal training, group fitness classes, and educational workshops. Dr. Gentile leads the Walk with a Doc Highland Park chapter, active since spring 2020, and serves on the Community Advisory Board for Carlow College's Occupational Therapy program. She currently accepts Lifestyle Medicine Consultations and is not taking new primary care patients.
Education & Training
Undergraduate
St. Vincent College, B.S. Biology (2007-2010)
Medical School
University of Pittsburgh School of Medicine
Residency
Family Medicine, Mayo Clinic (completed 2017)
Certifications
Conditions Treated
Who is Dr. Gentile right for?
Dr. Gentile is an excellent fit for patients motivated to address the root causes of chronic disease. Adults managing diabetes, pre-diabetes, hypertension, or obesity benefit from her evidence-based lifestyle medicine approach. She works especially well with patients who want to reduce or eliminate medications through nutrition, movement, and behavioral change. Currently, she accepts new patients for Lifestyle Medicine Consultations rather than ongoing primary care.
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Frequently Asked Questions
Dr. Gentile treats diabetes, pre-diabetes, hypertension, obesity, and chronic disease. She applies evidence-based lifestyle interventions alongside primary care to target underlying causes rather than symptoms alone.
Dr. Gentile is not currently accepting new primary care patients. She does accept patients for Lifestyle Medicine Consultations. Contact the practice for current availability and scheduling.
Lifestyle Medicine uses evidence-based interventions in nutrition, movement, restorative sleep, stress management, social connection, and substance avoidance to prevent and treat chronic disease. Dr. Gentile holds board certification in Lifestyle Medicine from the American Board of Lifestyle Medicine and devotes significant time to studying and applying these principles with her patients.
Dr. Gentile earned her medical degree from the University of Pittsburgh School of Medicine in 2014. She completed her Family Medicine residency at Mayo Clinic in 2017 and stayed on as an attending physician in Mayo's Department of Family Medicine in Rochester, Minnesota through 2019.
Rebel Wellness is a lifestyle medicine-oriented wellness space Dr. Gentile opened in Pittsburgh's East End in 2023. It offers teaching kitchen classes, personal training, group fitness classes, educational workshops, and an on-demand library of resources.
Yes. Dr. Gentile leads the Walk with a Doc Highland Park chapter, which has been active since spring 2020. She serves on the Community Advisory Board for Carlow College's Occupational Therapy program and is a board member for Plant Based Pittsburgh.
Doctor profile last updated March 22, 2026