Roper St. Francis Physician Partners Signature Primary Care
Quick Facts
| Practice Type | Concierge |
| Location | Charleston, Lowcountry |
| Doctors | Vanessa McPherson MD, Family Medicine |
About
At Roper St. Francis Physician Partners Signature Primary Care, Dr. Vanessa McPherson delivers concierge-style primary care to patients in Charleston, SC. The practice operates on Kiawah Island and currently accepts new patients. Roper St. Francis Physician Partners has served Lowcountry families for generations, and Signature Primary Care carries that tradition forward with a more personalized structure.
The practice centers on the Signature Wellness Exam, a comprehensive two-visit assessment covering physical, mental, emotional, social, and sexual health. Dr. McPherson also evaluates nutrition, exercise, and sleep as part of each patient's full picture. Members receive 60-minute appointments, same-day or next-day scheduling, and 24/7 direct access to Dr. McPherson. She coordinates care with specialists across the Roper St. Francis Physician Partners network. Each patient leaves with a Personalized Wellness Program built around their individual health goals.
Details
Our Doctors
Similar Practices Nearby
Access Healthcare
Family Medicine, Preventive Medicine, Executive Health, Primary Care, Internal Medicine, Pediatrics
Sarah E. Stapleton, MD
Internal Medicine
Pullano Family Medicine
Family Medicine
Explore More
Frequently Asked Questions
The annual membership fee at Signature Primary Care is $3,000. That fee covers the Signature Wellness Exam, expanded lab testing, and screenings not covered by insurance. It also includes same-day scheduling and 24/7 direct access to Dr. McPherson.
No. The membership fee covers the Signature Wellness Exam and the access benefits of the program. Regular in-office visits, procedures, and sick care bill through your health insurance, including any applicable co-pays and deductibles, just as they would at a standard primary care practice.
Signature Primary Care accepts most major insurance plans for covered services such as sick visits, chronic disease management, and in-office procedures. The annual membership fee itself does not run through insurance.
The Signature Wellness Exam is a comprehensive two-visit assessment. During the first visit, you complete a wellness questionnaire and provide bloodwork, including advanced lipid, inflammation, and hormonal testing. During the second visit, Dr. McPherson reviews your results, checks your vaccine status, performs a head-to-toe physical, and conducts screenings for vision, hearing, peripheral vascular disease, dementia, lung function, grip strength, and body composition.
Call the practice at (843) 724-1900 to schedule a free 20-minute meet-and-greet with Dr. McPherson. During that conversation, she shares her care philosophy and you discuss whether the program fits your needs. You can join on-site or call back later to enroll over the phone.
Yes. Signature Primary Care offers same-day and next-day appointments to all members. To schedule, call the office at (843) 724-1900.
Standard appointments run 60 minutes. That length allows Dr. McPherson to address your concerns thoroughly and without rushing.
Yes. The practice offers virtual visits for appropriate care needs. Members can also communicate with Dr. McPherson through the MyChart patient portal.
The practice sits at 660 Freshfields Drive, Suite 210, on Kiawah Island, SC 29455. Dr. McPherson conducts all appointments at this location.
Signature Primary Care accepts payment by check or credit card for the annual membership fee.
Practice last updated April 4, 2026