Mission Metabolic Health
Quick Facts
| Practice Type | Concierge |
| Location | St. Clair Shores, Grosse Pointe City, Grosse Pointe Park, Grosse Pointe Farms, Grosse Pointe Shores, Grosse Pointe Woods, Macomb County, Harper Woods, Detroit, Clinton Township, Roseville, Metro Detroit |
| Doctors | Sean Cassleman DO, Internal Medicine |
| Telehealth Type | Video visits; virtual care available in Michigan, Florida, Tennessee, Texas |
| Insurance Accepted | Insurance accepted (specific plans not listed) |
| Telehealth Available | Yes |
About
At Mission Metabolic Health, Dr. Sean Cassleman delivers concierge internal medicine with a sharp focus on longevity, metabolic health, and proactive disease prevention. The St. Clair Shores practice operates on a guiding principle: Live Leaner, Longer, Better. Dr. Cassleman built the practice after more than a decade treating patients across Saint Clair Shores and Detroit, where he witnessed the toll of preventable chronic disease firsthand. Mission Metabolic Health stands apart through its multidisciplinary setup. An on-site gym supports supervised strength and fitness training alongside physician-led care, nutrition coaching, and advanced diagnostics. The practice holds the distinction of being the only Michigan participant in the Onero osteoporosis program, a research-based exercise protocol grounded in the LIFTMOR trial. Members receive advanced lab testing, body composition analysis, cardiovascular risk assessment, hormone therapy, and cancer screening options including whole body MRI and liquid biopsy. Dr. Cassleman also serves patients virtually across Florida, Tennessee, and Texas.
Details
Address
21444 Harper Ave., St. Clair Shores, MI 48080
Phone
(586) 200-4265Website
Visit websiteMembership Details
Membership fees structured to qualify as eligible medical expenses payable through HSA, HRA, FSA, or MSA funds, as well as deductible self-employed healthcare expenses. Onero Osteoporosis Program: $379 pre-enrollment screening fee; 2-month minimum commitment at $375 total ($187.50/month, $23.43/session).
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Frequently Asked Questions
Mission Metabolic Health structures membership fees to qualify as eligible medical expenses payable through HSA, HRA, FSA, or MSA accounts. Self-employed members may also deduct fees as healthcare expenses. The practice accepts insurance and submits claims on behalf of members for covered services.
The Onero program requires a $379 pre-enrollment screening fee. 43 per session. Mission Metabolic Health is the only practice in Michigan participating in the Onero program.
Yes. Mission Metabolic Health offers same-day appointments for members. Direct access to Dr. Cassleman, including his personal cell phone and email, also means patients can reach him around the clock without navigating a standard office phone system.
Yes. Dr. Cassleman provides virtual care for patients in Michigan, Florida, Tennessee, and Texas. Patients in other states can request virtual care on a case-by-case basis.
Mission Metabolic Health pairs physician-led medical care with an on-site gym, nutrition coaching, and a clinical team. Dr. Cassleman uses advanced diagnostics well beyond standard panels, including whole body MRI, liquid biopsy, NMR lipid profiles, and body composition scanning. Members also receive 24/7 direct access to Dr. Cassleman by phone and email.
Mission Metabolic Health offers whole body MRI and liquid biopsy for advanced cancer detection. Dr. Cassleman coordinates these screenings as part of a proactive, early-detection approach rather than waiting for standard screening age thresholds to trigger evaluation.
Yes. The practice includes an on-site gym where members undergo supervised strength training, mobility work, and cardiorespiratory assessments. Fitness training integrates directly into clinical care rather than operating as a separate wellness add-on.
The Onero program is a scientifically backed, research-based exercise regimen for patients with osteoporosis or osteopenia, grounded in the LIFTMOR trial. Dr. Cassleman uses it to build bone strength through supervised high-intensity resistance and impact training. Mission Metabolic Health is the only practice in Michigan that participates in the program.
Yes. Mission Metabolic Health currently accepts new patients. Prospective patients can contact the practice directly or sign up through the patient portal to begin the enrollment process.
The practice offers four structured weight management programs ranging from intensive biweekly physician-led tracks to coach-focused plans with physician oversight. Dr. Cassleman manages GLP-1 medications as part of these programs and tailors each plan to the patient's goals, body composition data, and metabolic profile.
Practice last updated June 11, 2026