About
Dr. John Manire is a board-certified family physician and Doctor of Osteopathic Medicine practicing in Louisville, Kentucky. He earned his Bachelor of Arts in Vocal Music Performance, Magna Cum Laude, from Austin Peay State University in Clarksville, Tennessee. He then pursued two graduate degrees at the University of Louisville: a Master of Music in Vocal Performance and a Master of Science in Exercise Physiology. During his time there, he won the John Hawkins Essay Competition and received the Dean's Citation Award. Dr. Manire completed his medical degree at the University of Pikeville Kentucky College of Osteopathic Medicine, where he served as an OMT Fellow and earned the Fellow of the Year award.
A native of western Kentucky and long-time Louisville resident, Dr. Manire brings a broad and integrative skill set to his patients. He holds special training in the musculoskeletal system and performs osteopathic manipulative treatment, acupuncture, prolotherapy, and PRP injections in his practice. His clinical interests span preventive medicine, complementary and integrative medicine, transgender healthcare, and HIV/AIDS care. He cares for patients of all ages, from newborns to elderly adults. When a patient requires hospitalization, Dr. Manire visits them and coordinates their specialist care directly. Outside of medicine, he is passionate about music, dance, art, and history.
Education & Training
Undergraduate
Austin Peay State University, B.A. Vocal Music Performance (Magna Cum Laude)
Medical School
University of Pikeville, Kentucky College of Osteopathic Medicine
Fellowship
OMT Fellow, University of Pikeville Kentucky College of Osteopathic Medicine (Fellow of the Year)
Additional Training
University of Louisville, Masters of Music in Vocal Performance; University of Louisville, Masters of Science in Exercise Physiology
Certifications
Conditions Treated
Who is Dr. Manire right for?
Dr. Manire is a strong fit for patients who want a single physician to handle the full range of primary care needs, from well-child visits to chronic disease management. Adults managing hypertension, diabetes, obesity, or heart disease benefit from his preventive and integrative approach. Patients seeking care for HIV/AIDS, transgender health, or LGBTQ-specific concerns will find knowledgeable, affirming care here. Those dealing with musculoskeletal pain, sports injuries, or chronic discomfort have access to OMT, prolotherapy, dry needling, and acupuncture alongside conventional treatment.
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Frequently Asked Questions
Dr. Manire treats a wide range of acute and chronic conditions. His focus areas include hypertension, diabetes, obesity, heart disease, and respiratory conditions. He also provides care for musculoskeletal conditions, HIV/AIDS, and transgender health needs. His background in exercise physiology and osteopathic medicine strengthens his approach to both prevention and chronic disease management.
Yes, Dr. Manire holds board certification as a family physician. He completed his medical training at the University of Pikeville Kentucky College of Osteopathic Medicine and served as an OMT Fellow, earning the Fellow of the Year award.
Dr. Manire performs osteopathic manipulative treatment, acupuncture, acupressure, prolotherapy with dextrose, platelet rich plasma prolotherapy, dry needling, trigger point injections, and extracorporeal pulse wave therapy. He also uses electrical stimulation, ultrasound therapy, and steroid joint injections. These therapies complement his conventional family medicine practice for patients managing pain or musculoskeletal conditions.
Yes. Dr. Manire provides affirming care for LGBTQ patients, including dedicated transgender healthcare services. He also offers HIV/AIDS care and stays current on public health topics relevant to the LGBTQ community.
Dr. Manire earned a Bachelor of Arts in Vocal Music Performance from Austin Peay State University, graduating Magna Cum Laude. He completed two graduate degrees at the University of Louisville: a Master of Music in Vocal Performance and a Master of Science in Exercise Physiology. He received his medical degree from the University of Pikeville Kentucky College of Osteopathic Medicine, where he was named OMT Fellow of the Year.
Yes. When members require hospitalization, Dr. Manire visits them and coordinates their care with specialists. He acts as a central point of contact to keep care organized and continuous across settings.
Yes. Members reach Dr. Manire directly by phone, text, or email outside of regular office hours. He provides his personal cell phone number to members for after-hours access.
Yes. Dr. Manire cares for patients across the full age range, from newborns through elderly adults. He performs well-child exams, sports and school physicals, and manages adult chronic and acute conditions.
Doctor profile last updated March 26, 2026