About
Glea Mazzuca, DO grew up in Albania and immigrated to the United States in 2003. She graduated from Temple University in 2008 with a Bachelor in Biochemical Sciences and a minor in Italian Literature, then earned her medical degree from Philadelphia College of Osteopathic Medicine in 2012. She completed her Internal Medicine residency at Aria Health, now Jefferson Northeast Hospital, in 2016. She holds board certification in Internal Medicine and maintains active membership in the American Osteopathic Association, the Pennsylvania Osteopathic Medical Association, and the American College of Osteopathic Internists.
After residency, Dr. Mazzuca worked as a nocturnist managing acute and chronic illness at Aria Frankford hospital. She later joined Christiana Care as a Hospitalist in 2018. Most recently, she practiced at Christiana Primary Care in Kennett Square before joining Reinvented Health in 2024. She takes a holistic approach rooted in Osteopathic principles and focuses on guiding patients toward longer, healthier lives. Outside the office, she practices yoga, travels, and pursues amateur photography. She lives in the Glen Mills area with her husband and three young children.
Education & Training
Undergraduate
Temple University, Bachelor in Biochemical Sciences, 2008
Medical School
Philadelphia College of Osteopathic Medicine, DO, 2012
Residency
Internal Medicine Residency, Aria Health (Jefferson Northeast Hospital), completed 2016
Certifications
Conditions Treated
Who is Dr. Mazzuca right for?
Dr. Mazzuca is a strong fit for adults managing chronic conditions or looking to strengthen their long-term health. Patients with complex medical histories benefit from her hospitalist background and osteopathic approach. She works well with adults who want a physician focused on prevention and whole-body wellness. Her training in internal medicine makes her effective with multi-system conditions.
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Frequently Asked Questions
Dr. Mazzuca specializes in internal medicine, primary care, and preventive medicine. She focuses on managing both acute illness and chronic conditions. Her osteopathic training shapes a whole-body approach to diagnosis and treatment.
Yes, Dr. Mazzuca holds board certification in Internal Medicine. She earned her DO from Philadelphia College of Osteopathic Medicine and completed her residency at Aria Health, now Jefferson Northeast Hospital.
Dr. Mazzuca has experience in hospital medicine, having worked as a nocturnist at Aria Frankford Hospital and as a hospitalist at Christiana Care. She later moved into outpatient primary care at Christiana Primary Care in Kennett Square before joining Reinvented Health in 2024.
Dr. Mazzuca takes a holistic approach rooted in osteopathic principles. She focuses on guiding patients toward longer, healthier lives by addressing the whole person rather than isolated symptoms.
Dr. Mazzuca holds active membership in the American Osteopathic Association, the Pennsylvania Osteopathic Medical Association, and the American College of Osteopathic Internists.
Dr. Mazzuca attended Temple University for her undergraduate degree and earned her DO from Philadelphia College of Osteopathic Medicine in 2012. She completed her Internal Medicine residency at Aria Health, now Jefferson Northeast Hospital, in 2016.
Doctor profile last updated March 21, 2026