
Spruce MD
Quick Facts
| Practice Type | Hybrid |
| Location | Greenville |
| Doctors | Mary Brittain Blankenship MD, Functional Medicine |
About
At Spruce MD in Greenville, SC, Dr. Mary Brittain Blankenship leads an integrative and functional medicine practice built around proactive, personalized care. The practice takes a whole-person approach to health, focusing on longevity and optimal function rather than reactive disease management. Spruce MD operates as a cash-pay practice and does not accept insurance, keeping the relationship direct between patient and provider.
New patient visits run up to 60 minutes, and patients can message providers directly without delays. The clinical scope is broad: primary care, men's and women's health, hormone therapy, thyroid and cholesterol management, weight management, and continuous glucose monitoring sit alongside longevity testing tools including DEXA body scans, VO2 max testing, and resting metabolic rate testing. Spruce MD also offers nutrition and dietitian services, health coaching, and a full medical aesthetics menu. The practice participates actively in the Greenville community, including the Ride to End Alzheimer's cycling event and collaborative events with local wellness partners.
Details
Website
Visit websiteMembership Details
Cash-pay practice; membership plans available (details on /plans page, content not loaded). New patient visits up to 60 minutes. General public event tickets $30; Spruce MD members free.
Typical Appointment
60 minutes
Our Doctors
Similar Practices Nearby

Ember Modern Medicine
Family Medicine, Primary Care, Preventive Medicine

Oakview Medical Associates
Family Medicine, Functional Medicine, Preventive Medicine

Forum Health Greenville
Family Medicine, Functional Medicine, Preventive Medicine
Explore More
Frequently Asked Questions
Spruce MD does not accept insurance. The practice operates as a cash-pay model, which keeps the relationship direct between patient and provider. Membership plans are available for patients who want ongoing care.
New patient visits at Spruce MD run up to 60 minutes. Follow-up appointments also receive ample time. The practice builds this time into its model so visits feel thorough rather than rushed.
Spruce MD extends well beyond standard primary care. The practice addresses hormone therapy, thyroid disease, cholesterol management, weight management, men's and women's health, erectile dysfunction, and continuous glucose monitoring. It also offers longevity testing, sports performance assessment, nutrition services, health coaching, and medical aesthetics.
Spruce MD offers DEXA body scanning, VO2 max testing, and resting metabolic rate testing. DEXA scanning measures bone mineral density, body fat distribution, and lean body mass. These tools give patients a detailed, data-driven baseline for tracking long-term health and physical performance.
Yes. Spruce MD patients reach their providers directly without a middleman or communication delays. This direct access is a built-in feature of how the practice operates, not an add-on.
Yes. The practice offers dedicated nutrition and dietitian services alongside a structured weight management program. Patients work with providers who integrate dietary guidance directly into their overall care plan.
Spruce MD provides skin consultations, facial and skin treatments, and brow, lash, and hair removal services. The practice takes an integrative view of skin health, connecting aesthetic care to internal factors like hormones, gut health, and nutrition.
Prospective patients can book a new patient appointment directly through the Spruce MD website. The practice offers separate booking tracks for medical care, nutrition, aesthetics, longevity testing, and blood draws. Membership plan options are also available for patients seeking ongoing care.
Yes. Spruce MD participates in Greenville community events and has hosted its own gatherings, including a skincare-focused social event in partnership with Städa Skin Lab. The practice has also participated in the Ride to End Alzheimer's cycling event and the Greenville Cycling Classic.
Practice last updated September 17, 2026
