About
Dr. Mary Brittain Blankenship is the physician behind Spruce MD, an integrative and functional medicine practice in Greenville, SC. Her clinical focus spans functional medicine, preventive medicine, men's and women's health, and longevity. She takes a root-cause approach to care, working to understand the internal factors driving each patient's health picture rather than treating symptoms in isolation.
Dr. Blankenship holds a deep interest in the connection between skin health and systemic internal factors, a topic she has presented on publicly at community events. She has been featured in Town Magazine for her perspective on clean eating and practical nutrition. She participates in community health initiatives including the Ride to End Alzheimer's and local cycling events. Patients at Spruce MD reach her directly, without the delays of a traditional office model.
Who is Dr. Blankenship right for?
Dr. Blankenship works well with adults who want a thorough, proactive approach to their health. Patients managing hormone imbalances, thyroid disease, or cholesterol benefit from her functional medicine lens. She serves both men and women, including men who want cardiovascular and metabolic risk addressed early. People interested in body composition, longevity testing, or optimizing physical performance find her scope of services a strong fit.
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Frequently Asked Questions
Dr. Blankenship focuses on functional and preventive medicine, with clinical depth in hormone therapy, thyroid disease, cholesterol management, and men's and women's health. She also addresses metabolic health, weight management, and erectile dysfunction as a cardiovascular risk indicator. Her approach seeks root causes rather than symptom management alone.
Yes. Dr. Blankenship has a dedicated men's health focus and addresses conditions men often delay addressing, including low testosterone and erectile dysfunction. She frames erectile dysfunction as a meaningful early signal of cardiovascular risk, making preventive care actionable and relevant for male patients.
Dr. Blankenship takes an integrative view of skin health, examining how internal factors such as gut health, hormones, and nutrition affect what happens at the skin level. She has presented publicly on this topic and incorporates it into both her medical and aesthetics services at Spruce MD.
Yes. Dr. Blankenship uses DEXA body scans, VO2 max testing, and resting metabolic rate testing as part of her longevity and performance health toolkit. DEXA scanning measures bone mineral density, body fat distribution, and lean body mass, giving patients a precise baseline for tracking health over time.
Dr. Blankenship integrates nutrition as a core element of her clinical work. Spruce MD offers dedicated nutrition and dietitian services alongside medical care. She has spoken publicly on practical clean eating and explores topics like the Mediterranean diet, intermittent fasting, and the gut-brain connection in her clinical thinking.
Yes. Spruce MD patients can message providers directly without going through a middleman or waiting for a callback. This direct access is a core part of how the practice operates.
Yes. Dr. Blankenship oversees both medical and aesthetic services at Spruce MD. The practice offers skin consultations, facial and skin treatments, and brow, lash, and hair removal services alongside its medical offerings.
Doctor profile last updated September 17, 2026