About
Dr. Mark Scheperle is a board-licensed internal medicine physician based in Saint Louis, Missouri. He earned his Doctorate of Medicine from the University of Missouri-Kansas City School of Medicine in 1989. He then completed both his internship and internal medicine residency at St. Mary's Health Center, St. Louis University, finishing in 1992.
Since 1992, Dr. Scheperle has served as Associate Professor of Clinical Medicine at Washington University School of Medicine. He has held the role of Medical Director at the University of Central Missouri since 2000. He maintains affiliations with the American College of Physicians, the American Medical Association, the American Academy of HIV Medicine, and several Missouri and St. Louis medical societies. Dr. Scheperle closely monitors his patients and collaborates with them to stay on a clear pathway toward wellness. He delivers care that is individualized, timely, and built around each patient's long-term health goals.
Education & Training
Medical School
University of Missouri-Kansas City School of Medicine, Doctorate of Medicine, 1989
Residency
Internal Medicine, St. Mary's Health Center, St. Louis University, 1990-1992
Additional Training
Internship: St. Mary's Health Center, St. Louis University, 1989-1990
Who is Dr. Scheperle right for?
Dr. Scheperle is a strong fit for adults who want a physician deeply engaged in their long-term health. Patients managing chronic conditions benefit from his proactive, monitoring-focused approach. He works well with individuals who want 24/7 physician access and same- or next-day appointment availability. Adults with complex or rare health histories find his thorough, collaborative style especially valuable. His MDVIP membership also suits patients who travel frequently and need coordinated care on the road.
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Frequently Asked Questions
Dr. Scheperle specializes in internal medicine. He focuses on preventive care, chronic disease management, and individualized wellness planning. He treats adult patients across a broad range of health concerns and builds long-term relationships with each person in his practice.
Dr. Scheperle holds licensure in Missouri and has practiced internal medicine since completing his residency at St. Mary's Health Center, St. Louis University in 1992. He is a member of the American College of Physicians and the American College General Practitioners-Diplomate.
Dr. Scheperle earned his medical degree from the University of Missouri-Kansas City School of Medicine in 1989. He completed his internship and internal medicine residency at St. Mary's Health Center, St. Louis University in St. Louis, finishing in 1992.
Yes. Dr. Scheperle has served as Associate Professor of Clinical Medicine at Washington University School of Medicine since 1992. He has also served as Medical Director at the University of Central Missouri since 2000.
Dr. Scheperle holds affiliations at St. Luke's Hospital, Barnes Jewish Hospital, and St. Mary's Health Center in the St. Louis area. These affiliations allow him to coordinate hospital-based care for his patients when needed.
Dr. Scheperle monitors his patients closely and collaborates with them to maintain progress toward their health goals. He aims to anticipate each patient's evolving needs before problems develop. His care style is individualized, compassionate, and proactive.
Dr. Scheperle is a member of the American College of Physicians, the American Medical Association, the American Academy of HIV Medicine, the Missouri State Medical Association, and the St. Louis Metro Medical Association. He also belongs to the American College General Practitioners-Diplomate and the St. Louis Ambassadors.
Yes. Dr. Scheperle is reachable by phone after hours and on weekends. Members can contact him directly for urgent concerns without waiting for the next business day.
Doctor profile last updated April 9, 2026
