About
Dr. Antonette Brigidi is a board-certified internal medicine physician who grew up outside Philadelphia in a multigenerational Italian American household. That upbringing shaped her belief in long-term therapeutic relationships with patients and families. She earned her undergraduate degree in chemistry with Honors from The Johns Hopkins University and her medical degree from the University of Maryland School of Medicine. She completed her internship and Primary Care Residency in Internal Medicine at the Hospital of the University of Pennsylvania.
After early practice at Chester County Hospital, Dr. Brigidi returned to Penn as faculty in 2010. In 2020, Penn recruited her to serve as Chief Medical Officer of Penn Signature Services, where she co-directed Executive Health, the Penn Passport program, and Penn Global Medicine. She later served as Lead Physician for Penn Executive Health at the Perelman Center for Advanced Medicine. She holds board certification in Internal Medicine, a Diplomate designation from the American Board of Lifestyle Medicine, and Fellowship in the American College of Physicians. She co-directs the culinary medicine course at the Perelman School of Medicine and is passionate about gardening, cooking, and therapeutic lifestyle interventions.
Education & Training
Undergraduate
B.S. in Chemistry with Honors, The Johns Hopkins University
Medical School
University of Maryland School of Medicine
Residency
Postdoctoral Internship and Primary Care Residency in Internal Medicine, Hospital of the University of Pennsylvania
Certifications
Conditions Treated
Who is Dr. Brigidi right for?
Dr. Brigidi is a strong fit for adults seeking a thorough, relationship-centered approach to primary care. Executives and professionals benefit from her background leading Penn Executive Health programs. Patients with chronic conditions often find her focus on lifestyle and nutrition interventions valuable. Her Italian American upbringing instilled a deep belief in multigenerational family medicine, making her well-suited for patients who want a physician who knows their full history.
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Frequently Asked Questions
Dr. Brigidi treats a broad range of internal medicine and preventive health concerns. Her clinical focus includes chronic disease management, metabolic health, and executive wellness. She also brings expertise in lifestyle and culinary medicine as therapeutic tools for prevention and treatment.
Yes. Dr. Brigidi holds board certification in Internal Medicine. She also carries a Diplomate designation from the American Board of Lifestyle Medicine and holds Fellowship in the American College of Physicians.
Dr. Brigidi has extensive executive health experience from her time at Penn Medicine. Penn recruited her in 2020 as Chief Medical Officer of Penn Signature Services, where she co-directed Executive Health and the Penn Passport program. She later served as Lead Physician for Penn Executive Health at the Perelman Center for Advanced Medicine.
Dr. Brigidi uses lifestyle and culinary medicine as active treatment tools, not just adjuncts. She co-directs a culinary medicine course at the Perelman School of Medicine. Her approach addresses nutrition, cooking, and therapeutic lifestyle changes as part of each patient's care plan.
Dr. Brigidi earned her medical degree from the University of Maryland School of Medicine. She then completed her internship and Primary Care Residency in Internal Medicine at the Hospital of the University of Pennsylvania.
Dr. Brigidi grew up in a multigenerational Italian American household outside Philadelphia. That upbringing shaped her belief in long-term therapeutic relationships with patients and families. It also fueled her passion for nutrition and culinary medicine as foundations of good health.
Yes. Preventive medicine is a central part of Dr. Brigidi's clinical work. She combines comprehensive internal medicine with lifestyle and nutritional counseling to help patients stay ahead of chronic disease.
Doctor profile last updated March 21, 2026