
The San Francisco Institute for Integrative and Regenerative Medicine
Quick Facts
| Practice Type | Specialty |
| Doctors | Jake Wardwell D.O., Family Medicine |
| Year Founded | 2012 |
| Insurance Accepted | Aetna, Cigna, United, Blue Shield of California |
About
At The San Francisco Institute for Integrative and Regenerative Medicine, Dr. Jake Wardwell brings together functional medicine, regenerative orthopedics, and integrative aesthetics under one roof. The practice draws on both ancient healing traditions and modern clinical science. Dr. Wardwell holds board certifications in Integrative Family Medicine and Osteopathic Manipulative Medicine, along with specialized credentials in regenerative orthopedics and musculoskeletal sonography.
The practice takes a systems-oriented approach to health. Dr. Wardwell addresses digestive health, detoxification, cardiometabolic function, and hormonal balance. He uses advanced lab testing through Genova Diagnostics to evaluate hormones, minerals, amino acids, heavy metals, and pathogens. Musculoskeletal ultrasound guides regenerative injections and tracks healing progress. The practice also offers a broad aesthetic medicine program, including laser treatments, body contouring, and PRP-based therapies. SFIIRM accepts Aetna, Cigna, United, and Blue Shield of California for covered services.
Details
Address
450 Sutter Street, Suite 1341, San Francisco, CA 94109
Phone
(415) 606-0309Website
Visit websiteOur Doctors
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Frequently Asked Questions
The practice accepts Aetna, Cigna, United, and Blue Shield of California. Patients with these plans typically pay a copay at the time of their visit. If you carry a deductible, you may receive a bill at your plan's contracted rate until you meet it. The practice does not participate in Medicare or Medicaid networks.
Several services fall outside standard insurance coverage. These include Bio-Identical Hormone Therapy, Functional Medicine visits, Regenerative Injection Therapy, nitrous oxide sedation, supplements, and all aesthetic services. The practice accepts HSA and FSA payments for these non-covered services.
Yes. SFIIRM accepts HSA and FSA funds for services that insurance does not cover. This includes functional medicine consultations, regenerative injections, hormone therapy, and aesthetic treatments. Contact the office to confirm eligibility for a specific service before your appointment.
Regenerative injection therapy uses the body's own healing mechanisms to repair damaged tissue. Dr. Wardwell concentrates growth factors from the patient's blood and injects them into the target site. This approach supports healing in torn muscles, ligaments, and cartilage. The practice also applies the same growth factor principles to facial rejuvenation, hair regrowth, and scar removal. Musculoskeletal ultrasound guides each injection and tracks regenerative progress over time.
Dr. Wardwell takes a thorough history and performs an in-depth physical exam. He uses advanced lab testing through Genova Diagnostics to assess hormones, minerals, amino acids, heavy metals, toxins, pathogens, and digestive enzyme deficiencies. From those results, he builds a treatment plan that may include customized nutraceuticals, compounding pharmacy prescriptions, IV nutrient therapy, or dietary changes.
Yes. The practice uses the InBody 770 Body Composition Analyzer to measure bio-impedance without relying on population average calculations. It detects body fat, visceral fat, muscle mass, and markers of cellular integrity, inflammation, and swelling. Dr. Wardwell uses these results to guide treatment planning and track progress over time.
The practice offers a broad range of aesthetic services. These include Broadband Light Therapy, Halo Laser, SkinTyte, Contour TRL, Nano and Micro Peels, TruSculpt iD, TruSculpt Flex, Laser Lipolysis, Lipotherapy, Hair Regrowth, and the Priapus Shot. Dr. Wardwell also performs hyperbaric oxygen facials using the Intraceuticals Oxygen Facial machine. Many injection-based aesthetic procedures use ultrasound guidance for precision.
Dr. Wardwell works across a full spectrum of osteopathic techniques. These include Cranio-Sacral therapy, Counterstrain, Myofascial Release, Muscle Energy Technique, and High Velocity Low Amplitude adjustment. He selects the approach based on each patient's condition and tolerance.
New patients can book an appointment directly through the practice's online scheduling portal. The office operates Monday through Friday, 9am to 5pm. com. The practice is located at 450 Sutter Street, Suite 1341, in San Francisco.
Yes. Dr. Wardwell completed acupuncture training in both the United States and China, including a two-month intensive program at Shanghai University of Traditional Chinese Medicine. He offers acupuncture as a standalone treatment and integrates it with other therapies. Cosmetic acupuncture and facial rejuvenation are also part of the practice's clinical offerings.
Practice last updated March 21, 2026


