Defy of Indiana
Quick Facts
| Practice Type | Direct Primary Care |
| Location | Carmel, Indianapolis |
| Doctors | Tina Harrison M.D., Internal Medicine |
| Telehealth Type | Telehealth appointments (in-office and telehealth options mentioned) |
| Telehealth Available | Yes |
About
At Defy of Indiana, Dr. Tina Harrison leads a functional medicine practice built around root-cause care. The Carmel practice serves both men and women through two dedicated programs: DEFY for Women and DEFY for Men. Founder Amy Marckese, DDS, launched the practice after her own personal health transformation through hormone balancing, peptide therapy, and exercise.
The clinical scope at Defy of Indiana runs deep. Dr. Harrison brings board certification in internal medicine and more than 20 years of experience treating acute and chronic conditions. The practice takes a direct-pay approach, requiring no membership and no insurance. Patients pay only for the services they receive. Core offerings include bioidentical hormone replacement therapy, BioTE pellet therapy, peptide therapy, IV therapies, gut health testing, and weight loss support using semaglutide and tirzepatide. Licensed Esthetician LeeAnne Wheeldon delivers a full menu of aesthetic services, from Morpheus8 RF microneedling and Lumecca IPL to facials, chemical peels, and Dysport injections. The practice also offers telehealth appointments alongside in-office visits.
Details
Address
715 W. Carmel Drive, Unit 101, Carmel, IN 46032
Phone
(317) 361-4481Website
Visit websiteMembership Details
No Access Fee, No Membership Required. Pay Only for the Services You Receive. $375 deposit required when scheduling initial appointment, covering the first two visits: $200 for comprehensive initial consultation and $175 for the second follow-up session.
Our Doctors
Similar Practices Nearby
Verve Health
Primary Care, Functional Medicine
Imago Dei Restorative Health
Pediatrics, Functional Medicine, Preventive Medicine, Psychiatry
Valor Direct Primary Care
Family Medicine, Primary Care, Preventive Medicine
Explore More
Frequently Asked Questions
No. Defy of Indiana requires no membership and no access fee. You pay only for the services you receive. New patients schedule an initial appointment with a $375 deposit, which covers a comprehensive first consultation at $200 and a follow-up session at $175.
The practice does not accept insurance. Defy of Indiana operates on a direct-pay model. All fees go toward the specific services you choose. This structure allows the practice to focus entirely on your care without insurance restrictions shaping treatment decisions.
Defy of Indiana currently accepts new patients. You can schedule by calling or texting (317) 361-4481, or by submitting a request through the website. A $375 deposit secures your first two appointments: the comprehensive initial consultation and your first follow-up visit.
Yes. The practice offers both in-office and telehealth appointments. com.
The practice offers bioidentical hormone replacement therapy for both men and women. Defy of Indiana holds BioTE certification and provides BioTE pellet therapy specifically. The team also performs hormone testing and thyroid optimization as part of a comprehensive hormone care approach.
Yes. The practice offers medically supervised weight loss support, including semaglutide and tirzepatide. The team also uses peptide therapy, LipoMino injections, InBody body composition testing, and health coaching to support weight and metabolic goals.
Licensed Esthetician LeeAnne Wheeldon provides a full range of aesthetic treatments at the practice. Services include Morpheus8 RF microneedling, Morpheus8 Body, Lumecca IPL, DiolazeXL laser hair removal, Dysport neurotoxin injections, chemical peels, dermaplaning, microneedling with Rejuvapen, and facials. The practice also carries medical-grade skincare lines including Neova, Alastin, and Ourself Skincare.
The practice uses GI-MAP stool testing, a DNA-based analysis that evaluates the gastrointestinal microbiome in detail. Results guide personalized treatment plans that may include nutraceuticals, supplements, and dietary guidance to restore digestive balance.
Yes. The practice offers dedicated programs for each. DEFY for Women addresses hormone imbalance, energy, mood, weight, and sexual health. DEFY for Men focuses on testosterone, muscle mass, energy, and overall vitality. Both programs draw on the same functional medicine framework.
The practice operates Monday through Friday from 8:30 AM to 4:30 PM. The office sits at 715 W. Carmel Drive, Unit 101, in Carmel, Indiana. Telehealth visits extend access for patients who prefer remote appointments.
Practice last updated March 21, 2026