About
Dr. William Epperly has practiced family and functional medicine since earning board certification as a family practitioner in 1985. He earned his MD from the University of Illinois College of Medicine at Peoria and his undergraduate degree from Augustana College. He completed his family practice residency at St. Joseph Hospital in Chicago, where he served as Co-Chief Resident.
Dr. Epperly holds membership in the American Academy of Family Physicians, The Menopause Society, and the Obesity Medicine Association. He specializes in thyroid disorders, menopause, and hormone imbalances, using bioidentical hormone replacement therapy among other treatment approaches. His clinical interests extend to autoimmune disorders, gut health, chronic fatigue, and food allergies and sensitivities. He builds individualized care plans and works closely with patients to address complex, often interrelated health concerns across every stage of life.
Education & Training
Undergraduate
Augustana College, BA
Medical School
University of Illinois College of Medicine at Peoria
Residency
Family Practice, St. Joseph Hospital, Chicago (Co-Chief Resident)
Certifications
Conditions Treated
Who is Dr. Epperly right for?
Dr. Epperly is a strong fit for adults dealing with hormone imbalances, thyroid disorders, or menopause symptoms. Patients navigating chronic fatigue, autoimmune conditions, or gut health problems benefit from his root-cause approach. He also works well with individuals seeking medical weight loss or testosterone replacement therapy. Those who want a thorough diagnostic workup before starting treatment will appreciate his use of advanced testing.
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Frequently Asked Questions
Dr. Epperly specializes in thyroid disorders, hormone imbalances, and menopause. He also treats autoimmune disorders, leaky gut, chronic fatigue, and food allergies and sensitivities. He takes a functional medicine approach to each of these conditions, using advanced diagnostics to identify root causes before building a care plan.
Yes, Dr. Epperly holds board certification as a family practitioner. He earned that certification in 1985 and has practiced continuously since. He also carries the FAAFP designation from the American Academy of Family Physicians.
Dr. Epperly earned his MD from the University of Illinois College of Medicine at Peoria. He completed his family practice residency at St. Joseph Hospital in Chicago, where he served as Co-Chief Resident. His undergraduate degree comes from Augustana College.
Yes, Dr. Epperly offers bioidentical hormone replacement therapy as part of his hormone health services. He uses BHRT to address menopause, andropause, and other hormone imbalances. The practice also delivers testosterone replacement through pellets implanted under the skin.
Dr. Epperly holds membership in the American Academy of Family Physicians, The Menopause Society, and the Obesity Medicine Association. These affiliations reflect his focus on hormone health, menopause care, and weight management alongside his broader functional medicine practice.
Dr. Epperly addresses gut health through functional testing and personalized treatment plans. He treats conditions such as leaky gut and uses the clinic's Gut Detox Program to support digestive recovery. He also uses gastrointestinal effects testing and small intestine bacterial overgrowth testing to guide care.
Yes, Dr. Epperly treats chronic fatigue as part of his functional medicine practice. He uses specialized chronic fatigue testing to identify underlying contributors, which may include hormonal imbalances, immune dysfunction, or chronic infections. He then builds a targeted care plan based on each patient's results.
Dr. Epperly uses a broad panel of advanced diagnostics, including adrenal saliva testing, thyroid testing, blood hormone testing, mycotoxin testing, heavy metals toxicity testing, genetic testing, and organic acid testing, among others. These tests help him identify root causes before recommending treatment.
Doctor profile last updated April 11, 2026