About
Dr. Roderick Santa Maria trained at New York University School of Medicine before completing his residency at Case Western Reserve University Hospital. He holds board certification in Internal Medicine and has practiced clinical medicine for more than 30 years. Over that career, he has performed well over 150,000 patient examinations and hospital visits. He has served as an attending physician at Boca Raton Regional Hospital for 38 years.
Dr. Santa Maria built his reputation on prevention. He pursues every avenue, holistic, nutritional, or medicinal, that research supports for keeping patients well. He carries nationally recognized expertise in Dysautonomia and POTS, Mast Cell Activation Syndrome, gastroparesis, and Ehlers-Danlos Syndrome. He prescribes intravenous saline therapy for POTS patients and partners with leading specialists nationwide for complex chronic illness cases. He also offers a case history review service, applying decades of clinical experience to patients with long-unresolved diagnoses. He hosts POTS and Dysautonomia support groups at Boca Raton Regional Hospital and leads online webinars for the broader patient community. Patients who come to him in their 40s and 50s regularly thrive into their 80s and 90s under his care.
Education & Training
Medical School
New York University School of Medicine (MD)
Residency
Case Western Reserve University Hospital
Additional Training
Attending physician at Boca Raton Regional Hospital for 38 years
Certifications
Conditions Treated
Who is Dr. Santa Maria right for?
Dr. Santa Maria is an excellent fit for adults managing complex chronic conditions such as POTS, MCAS, or gastroparesis. Patients carrying long-unresolved diagnoses benefit from his case history review service and decades of clinical experience. He also works well with adults in their 40s and 50s who want a prevention-focused physician for the long term. His concierge model gives patients direct access to him after hours and on weekends. Anyone seeking a physician who pursues both functional and conventional approaches will find his practice a strong match.
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Frequently Asked Questions
Dr. Santa Maria holds nationally recognized expertise in Dysautonomia and POTS, Mast Cell Activation Syndrome, gastroparesis, and Ehlers-Danlos Syndrome. He also focuses on cardiovascular disease prevention, lipid management, and chronic illness management. He pursues holistic, nutritional, and medicinal approaches supported by research.
Yes. Dr. Santa Maria holds board certification in Internal Medicine. He trained at New York University School of Medicine and completed his residency at Case Western Reserve University Hospital.
Dr. Santa Maria has practiced clinical medicine for more than 30 years. He opened Santa Maria Medicine in Boca Raton in 1987 and has served the same South Florida community ever since. He has also served as an attending physician at Boca Raton Regional Hospital for 38 years.
Yes. Dr. Santa Maria prescribes intravenous saline therapy for patients with POTS. He administers this treatment in-office and combines it with a comprehensive management approach tailored to each patient's condition.
Yes. Dr. Santa Maria offers a dedicated case history review service for patients with long-unresolved diagnoses. He applies more than 30 years of clinical experience to these cases. For the most intricate diagnostic challenges, he also partners with leading specialists across the country.
Yes. Dr. Santa Maria hosts POTS and Dysautonomia support groups at Boca Raton Regional Hospital. He also leads online webinars for the broader patient community. These resources extend his care beyond the individual appointment.
Dr. Santa Maria built his reputation on stopping disease before it becomes serious. He pursues every avenue, holistic, nutritional, or medicinal, that research supports. Patients who begin care with him in their 40s and 50s regularly thrive into their 80s and 90s.
Dr. Santa Maria earned his MD at New York University School of Medicine. He completed his residency at Case Western Reserve University Hospital. Both institutions rank among the country's leading medical training programs.
Doctor profile last updated March 21, 2026