About
Matthew L. Mintz, MD, FACP, is a board-certified internist with over 27 years of experience in internal medicine. He earned his medical degree from George Washington University School of Medicine and spent two decades there as a full-time clinician and faculty member before opening his own practice. He holds hospital privileges at George Washington University Hospital and Suburban Hospital in Bethesda. He continues as Clinical Associate Professor at GWU School of Medicine, supervising medical students during their third-year primary care clerkship.
Washingtonian Magazine has named Dr. Mintz a Top Doc every year since 2012. He holds Fellowship status in the American College of Physicians and has published research on chronic diseases including diabetes, asthma, COPD, and obesity. His clinical passions span functional medicine, longevity and anti-aging medicine, Long COVID, bioidentical hormone replacement therapy, medical cannabis, and medical weight loss. He runs one of the area's few authorized Spravato treatment centers, prescribing and administering nasal esketamine for patients with treatment-resistant depression. A Montgomery County native, he lives in Rockville with his wife and two teenage daughters.
Education & Training
Medical School
George Washington University School of Medicine, Washington, D.C.
Additional Training
Clinical Associate Professor, George Washington University School of Medicine; Fellowship in the American College of Physicians (FACP)
Certifications
Conditions Treated
Who is Dr. Mintz right for?
Dr. Mintz is a strong fit for adults seeking a deeply experienced internist with a broad clinical range. Patients managing chronic conditions such as diabetes, asthma, COPD, or obesity benefit from his research-backed expertise. He is a good match for those pursuing longevity medicine, functional medicine, or bioidentical hormone therapy. Patients with treatment-resistant depression can access Spravato therapy through his authorized treatment center. He also serves patients navigating Long COVID or those interested in medical cannabis.
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Frequently Asked Questions
Dr. Mintz specializes in internal medicine with a strong focus on chronic disease management. His clinical expertise includes diabetes, asthma, COPD, and obesity. He also treats patients with Long COVID, treatment-resistant depression, and hormonal imbalances, and he offers longevity and anti-aging medicine.
Spravato is a nasal esketamine treatment for treatment-resistant depression. Dr. Mintz runs one of the area's few authorized Spravato treatment centers, prescribing and administering the therapy in-office. Patients who have not responded to standard antidepressants may be candidates for this treatment.
Yes, Dr. Mintz holds board certification in internal medicine. He also holds Fellowship status in the American College of Physicians, a distinction reserved for internists with demonstrated clinical excellence and scholarly achievement.
Dr. Mintz earned his medical degree from George Washington University School of Medicine. He then spent two decades there as a full-time clinician and faculty member before opening his Rockville practice. He continues as Clinical Associate Professor at GWU, supervising third-year medical students.
Yes, functional medicine and longevity medicine are among Dr. Mintz's core clinical passions. He takes an integrative approach, looking at root causes of chronic illness alongside advanced diagnostics. He also offers bioidentical hormone replacement therapy and medical weight loss as part of his preventive and anti-aging focus.
Yes, Washingtonian Magazine has named Dr. Mintz a Top Doc every year since 2012. He has also published research on chronic diseases including diabetes, asthma, COPD, and obesity. His long-standing academic ties to George Washington University further reflect his standing in the medical community.
Yes, Dr. Mintz includes medical cannabis among his clinical services. He evaluates patients for cannabis-based treatment options as part of his integrative and functional medicine approach.
Doctor profile last updated March 21, 2026