About
Dr. Leslie Meserve earned her Bachelor of Science at Vanderbilt University before returning to her hometown of Charleston for medical school at the Medical University of South Carolina. She completed her Internal Medicine residency at the University of California, Los Angeles, where she trained in both acute and primary care medicine. She holds board certification in Internal Medicine and serves as a Certified Menopause Practitioner and member of the Menopause Society.
Dr. Meserve established a busy primary care practice in Newport Beach in 2004. She later founded Framework Health to build something more personally meaningful. Turning 40 sharpened her focus: she became a healthy aging specialist and brought that perspective directly into her clinical work. She draws on Western Medicine, Functional Medicine, and Integrative Medicine to create personalized plans for each patient. Her clinical interests include hormone therapy, sleep, nutrition, exercise, and metabolic health. She sees patients in person and by telemedicine. As a wife and mother of two, she brings a grounded, real-world perspective to the health concerns her patients navigate every day.
Education & Training
Undergraduate
Vanderbilt University, B.S.
Medical School
Medical University of South Carolina
Residency
Internal Medicine, University of California, Los Angeles
Certifications
Conditions Treated
Who is Dr. Meserve right for?
Dr. Meserve works best with adults over 40 who want to take an active role in their health. Patients managing perimenopause, menopause, or low testosterone find her clinical depth especially valuable. She also serves patients dealing with chronic conditions like diabetes, hypertension, or hypothyroidism alongside aging-related concerns. Those seeking a personalized approach to weight management, hormone therapy, or metabolic health fit well with her practice.
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Frequently Asked Questions
Dr. Meserve focuses on healthy aging and treats a broad range of conditions. Her clinical expertise covers perimenopause and menopause, low testosterone in both men and women, diabetes, hypertension, hypothyroidism, osteoporosis, obesity, mood disorders, hot flashes, night sweats, and insomnia. She integrates Western, Functional, and Integrative Medicine to address each condition.
Yes. Dr. Meserve holds board certification in Internal Medicine. She also serves as a Certified Menopause Practitioner and is an active member of the Menopause Society.
Dr. Meserve earned her medical degree at the Medical University of South Carolina in Charleston. She completed her Internal Medicine residency at the University of California, Los Angeles. Before medical school, she earned a Bachelor of Science at Vanderbilt University.
Yes. Hormone therapy is one of Dr. Meserve's core clinical areas. She offers hormone replacement therapy for perimenopausal and postmenopausal women as well as men and women with low testosterone. She tailors every hormone plan to the individual patient and reassesses it regularly.
Yes. Dr. Meserve offers medically supervised weight management, including GLP-1 receptor agonist treatments such as semaglutide and tirzepatide. She pairs these approaches with nutrition counseling and personalized care planning to support sustainable results.
Yes. Dr. Meserve sees patients both in person at the Newport Beach office and by telemedicine. This flexibility allows her to support patients wherever they are.
Dr. Meserve builds personalized treatment plans that draw on Western Medicine, Functional Medicine, and Integrative Medicine. She begins with a thorough evaluation of hormone health, metabolism, sleep, bone density, and cardiovascular risk. She reassesses each plan regularly to ensure it continues to meet the patient's needs.
The majority of Dr. Meserve's patients are over 40. She focuses on adults who want to slow the effects of aging, manage chronic conditions, and optimize their overall vitality. She sees both men and women across a wide range of health concerns.
Doctor profile last updated April 27, 2026