About
Dr. Lenora Epple is an Internal Medicine physician practicing in Jefferson City, Missouri. She focuses on adult primary care across a wide clinical spectrum. Her work spans preventive visits, chronic condition management, medication review, and long-term wellness planning. She brings particular depth to hormone health, treating perimenopause, menopause, and low testosterone in both women and men. She also guides patients through medical weight loss, including GLP-1 medication management.
Dr. Epple's clinical interests extend to metabolic health, gut health, mood support, and conditions like thyroid disorders, insulin resistance, and iron deficiency anemia. She takes a whole-person approach, pairing clinical care with health coaching and nutrition guidance. Her 90-Day Signature coaching programs are physician-guided and built for everyday life. Outside the exam room, Dr. Epple has spoken at the Yellow Rose Luncheon Women of Achievement in Jefferson City. She actively shares health education with her community and currently accepts new patients.
Education & Training
Internal Medicine
Conditions Treated
Who is Dr. Epple right for?
Dr. Epple is a strong fit for adults managing chronic conditions like hypertension, diabetes, thyroid disorders, or metabolic syndrome. Women navigating perimenopause or menopause will find focused, individualized hormone care. Men dealing with low testosterone, low energy, or weight challenges benefit from her men's hormone evaluations. Patients with gut symptoms, mood concerns, or iron deficiency also fit naturally into her practice. Anyone who wants a physician who tracks their health over time, not just at sick visits, will find her approach well-suited to their needs.
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Frequently Asked Questions
Dr. Epple treats a broad range of adult conditions. Her clinical strengths include perimenopause and menopause, low testosterone, thyroid disorders, insulin resistance, prediabetes, diabetes, hypertension, high cholesterol, metabolic syndrome, and obesity. She also addresses gut health issues like IBS, reflux, and bloating, along with anxiety, depression, brain fog, sleep disorders, and iron deficiency anemia.
Yes, Dr. Epple offers hormone care for both. She provides personalized perimenopause and menopause consultations, including hormone replacement therapy for women. She also evaluates men for low testosterone and manages testosterone replacement therapy when appropriate.
Dr. Epple takes a physician-led approach to weight loss that addresses the full picture. She reviews weight history, metabolism, hormones, medications, sleep, and insulin resistance. She manages GLP-1 medications and builds individualized plans. Her 90-Day Signature coaching programs give patients structured, ongoing support.
Yes, Dr. Epple currently accepts new patients. Prospective patients can start with a complimentary 30-minute Health Clarity Session to explore whether the practice is the right fit before committing to a membership or visit.
Dr. Epple offers dedicated gut health consultations for patients managing bloating, constipation, diarrhea, reflux, nausea, or food-related symptoms. She takes a full hour to review symptoms and build a personalized plan. She connects gut health to broader concerns like mood, energy, and inflammation.
Yes, Dr. Epple provides mental health and mood support as part of her primary care practice. She evaluates and manages anxiety, depression, and brain fog, often exploring hormonal, metabolic, or nutritional contributors alongside traditional treatment approaches.
Yes, Dr. Epple runs physician-guided 90-Day Signature coaching programs. These programs focus on practical, sustainable health changes. Members also have access to health coaching as part of the Comprehensive Primary Care membership.
Dr. Epple keeps her panel small so she can give each patient meaningful time and consistent follow-through. She offers 60-minute appointments, direct phone and text access, and visits that extend to home or workplace settings. Her clinical focus covers both acute care and long-term wellness planning.
Doctor profile last updated August 17, 2026
