About
Dr. Leigh LoPresti graduated from the UVM College of Medicine in 1983 and completed his Family Medicine residency at the Medical Center Hospital of Vermont in 1986. He has held continuous board certification in Family Medicine ever since. His career spans nearly four decades and three distinct phases of practice. He worked in two HMOs in Massachusetts and Minnesota from 1986 to 1991. He then returned to Manchester Center for a decade of private practice before transitioning to teaching appointments from 2001 to 2010, where he mentored residents and medical students and completed a research fellowship. He has published nine articles in the medical literature.
Dr. LoPresti tells everyone he teaches that family medicine is the most fun you can have with a medical license. He founded Manchester Direct Family Practice in 2024, thrilled to return to a community he knows well. Born and raised on Long Island, he has called Vermont home for most of his career. He is a widower with two cherished daughters, and the family traveled together to all 50 states over 13 years. He pioneered a business membership model in the 1990s with the Vermont Country Store — a model that now underpins his current DPC practice.
Education & Training
Medical School
UVM College of Medicine, Class of 1983
Residency
Family Medicine, Medical Center Hospital of Vermont, completed 1986
Fellowship
Research fellowship (included during teaching appointments 2001–2010)
Additional Training
Teaching appointments for residents and medical students, 2001–2010
Certifications
Conditions Treated
Who is Dr. LoPresti right for?
Dr. LoPresti serves patients of all ages, from newborns through seniors. He treats a wide range of conditions including hypertension, diabetes, high cholesterol, thyroid disorders, asthma, depression, anxiety, migraines, and urinary incontinence. Patients who want a consistent relationship with one physician benefit most from his practice model. Those managing chronic conditions find his on-site medication dispensing and included lab tests especially practical. Adults seeking preventive care, urgent visits, or in-office procedures will find his full-spectrum approach a strong fit.
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Frequently Asked Questions
Dr. LoPresti treats a broad range of acute and chronic conditions. These include hypertension, diabetes, high cholesterol, thyroid disorders, asthma, urinary tract infections, gastroesophageal reflux, osteoporosis, depression, anxiety, migraines, urinary incontinence, and concussion. He provides full-spectrum family medicine for patients from newborns through seniors.
Yes. Dr. LoPresti holds continuous board certification in Family Medicine since 1986. He completed his residency at the Medical Center Hospital of Vermont and has maintained his certification without interruption throughout his career.
Dr. LoPresti earned his medical degree from the UVM College of Medicine in 1983. He completed his Family Medicine residency at the Medical Center Hospital of Vermont in 1986. He later completed a research fellowship during his teaching appointment years from 2001 to 2010.
Dr. LoPresti has practiced medicine for nearly four decades. His career includes time in HMO settings in Massachusetts and Minnesota, private practice in Manchester Center, academic teaching appointments, and various employed clinical roles before founding Manchester Direct Family Practice in 2024.
Yes. Dr. LoPresti provides care for patients across all life stages, from newborns to seniors. His training in family medicine covers pediatric, adult, and geriatric care.
Dr. LoPresti believes family medicine is one of the most meaningful and enjoyable fields in all of medicine. He focuses on knowing each patient well and addressing the full range of their health needs. He caps his panel at 600 patients to stay accessible and thorough with everyone he serves.
Yes. Dr. LoPresti has published nine articles in the medical literature. He also completed a research fellowship during his teaching appointment years from 2001 to 2010.
Yes. Members can text Dr. LoPresti directly after hours. He responds on weekdays from 7 AM to 9 PM and on weekends from 7 to 10 AM and 4 to 9 PM. This direct access is one of the core benefits of membership at Manchester Direct Family Practice.
Doctor profile last updated April 11, 2026