About
Dr. Lawrence Afrin graduated summa cum laude and as class valedictorian with a BS in Computer Science from Clemson University in 1984. He completed medical school, an internal medicine residency, and both clinical and research fellowships at the Medical University of South Carolina between 1984 and 1995. He then joined the MUSC Hematology/Oncology faculty, where he served for nearly two decades. During that time, he directed the hematology/oncology fellowship training program from 1997 to 2010 and led the Hollings Cancer Center's Myeloproliferative Neoplasms Clinical Trials Program from 2008 to 2014. His early interest in computer science also shaped a parallel career in medical informatics at MUSC.
In 2014, Dr. Afrin joined the University of Minnesota's Hematology/Oncology faculty to deepen his clinical and research work in mast cell disease. He joined the AIM Center team in 2017 and now focuses exclusively on MCAS and related conditions. He has authored and co-authored numerous publications on MCAS, including consensus statements on diagnostic criteria, and the field recognizes him as one of its foremost world experts. Dr. Afrin currently accepts new patients.
Education & Training
Undergraduate
BS in Computer Science (summa cum laude, valedictorian), Clemson University, 1984
Medical School
Medical University of South Carolina (MUSC), 1984-1995
Residency
Internal Medicine residency, Medical University of South Carolina (MUSC)
Fellowship
Clinical and research fellowships, Medical University of South Carolina (MUSC)
Additional Training
Hematology/Oncology faculty, MUSC; medical informatics career at MUSC; Hematology/Oncology faculty, University of Minnesota (2014)
Conditions Treated
Who is Dr. Afrin right for?
Dr. Afrin is the right fit for patients with Mast Cell Activation Syndrome or suspected mast cell disorders. He works well with complex cases that have gone undiagnosed or misdiagnosed elsewhere. Patients traveling from outside the region or internationally regularly seek his expertise. His exclusive focus on MCAS and related conditions means he brings deep, specialized knowledge to each case.
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Frequently Asked Questions
Dr. Afrin focuses exclusively on Mast Cell Activation Syndrome and related conditions. He has spent years building his clinical and research expertise in mast cell disease. He has authored numerous publications on MCAS, including consensus statements on diagnostic criteria, and the field recognizes him as one of its foremost world experts.
Yes, Dr. Afrin currently accepts new patients. All new patients begin with an initial consultation at the Purchase, NY location.
Dr. Afrin completed medical school, an internal medicine residency, and both clinical and research fellowships at the Medical University of South Carolina between 1984 and 1995. Before entering medicine, he graduated summa cum laude and as class valedictorian from Clemson University with a BS in Computer Science. He later joined the faculty at MUSC and then the University of Minnesota before joining AIM Center in 2017.
Dr. Afrin served on the MUSC Hematology/Oncology faculty for nearly two decades. He directed the hematology/oncology fellowship training program from 1997 to 2010. He also led the Hollings Cancer Center's Myeloproliferative Neoplasms Clinical Trials Program from 2008 to 2014. In 2014, he joined the University of Minnesota's Hematology/Oncology faculty before focusing his practice fully on mast cell disease at AIM Center.
Yes, Dr. Afrin has authored and co-authored numerous publications on Mast Cell Activation Syndrome. His work includes consensus statements on MCAS diagnostic criteria. He holds wide recognition in the field as one of its leading global experts.
Yes, AIM Center draws patients internationally, including from the UK, Israel, Australia, and France. Dr. Afrin sees patients with complex mast cell conditions regardless of where they live. All new patients visit the Purchase, NY location for their initial consultation.
Dr. Afrin builds individualized treatment plans that address root causes rather than symptoms alone. He applies both his deep research background and decades of clinical experience to each case. His approach reflects a functional medicine philosophy grounded in rigorous diagnostic evaluation.
Doctor profile last updated March 21, 2026