About
Dr. Kent Holtorf serves as Medical Director of Holtorf Medical Group and founder of Integrative Peptides. His clinical expertise spans tick-borne illness, chronic fatigue syndrome, fibromyalgia, CIRS, MCAS, long-COVID, TBI, PTSD, neurodegenerative diseases, and longevity medicine. He holds particular depth in hormone optimization, mitochondrial dysfunction, senolytic therapies, and immune modulation.
Dr. Holtorf has published two peer-reviewed studies demonstrating that TSH does not accurately reflect tissue thyroid hormone levels. He pioneered the clinical use of advanced peptide and bioregulator therapies, and practitioners worldwide now adopt his protocols. He has appeared on CBS 'The Doctors' and hosts the LA Integrative Doctors Meetup, an educational forum for physicians on peptide and bioregulator approaches. His work with veterans through the practice's dedicated Veterans Appreciation Program reflects a central part of his mission.
Conditions Treated
Who is Dr. Holtorf right for?
Dr. Holtorf is a strong fit for patients with complex, difficult-to-diagnose conditions. Those dealing with tick-borne illness, CIRS, chronic fatigue, fibromyalgia, or long-COVID benefit most from his approach. He also works with patients seeking hormone optimization, mitochondrial support, or longevity medicine. Veterans navigating chronic health conditions will find a dedicated program tailored to their needs.
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Frequently Asked Questions
Dr. Holtorf specializes in tick-borne illness, chronic fatigue syndrome, fibromyalgia, CIRS, MCAS, long-COVID, TBI, PTSD, and neurodegenerative diseases. He also treats hormone imbalances and mitochondrial dysfunction. His clinical approach focuses on identifying root causes behind complex, multisystem presentations.
Dr. Holtorf holds expertise in internal medicine, functional medicine, and preventive medicine. He also serves as founder of Integrative Peptides and has published peer-reviewed research on thyroid hormone physiology.
Dr. Holtorf has published two peer-reviewed studies demonstrating that TSH does not accurately reflect tissue thyroid hormone levels. This research informs his clinical approach to thyroid optimization and shapes protocols now used by practitioners worldwide.
Dr. Holtorf uses advanced peptide and bioregulator therapies, hormone optimization, senolytic therapies, and immune modulation strategies. He also incorporates comprehensive biomarker testing to guide treatment decisions. He pioneered many of the peptide protocols now in clinical use.
Yes, Dr. Holtorf leads a dedicated Veterans Appreciation Program at Holtorf Medical Group. This program reflects a central part of his mission and serves veterans managing chronic and complex health conditions.
Dr. Holtorf goes beyond standard TSH testing to evaluate actual tissue thyroid hormone levels. His published research demonstrates that TSH alone does not accurately reflect thyroid function. He uses this evidence base to guide more precise thyroid optimization for his patients.
' He also hosts the LA Integrative Doctors Meetup, an educational forum for physicians focused on peptide and bioregulator approaches.
Yes, Dr. Holtorf sees patients both in person at the El Segundo location and through virtual appointments. Patients can discuss which option suits their situation when they contact the practice.
Doctor profile last updated March 21, 2026