About
Dr. Justine DeCastro is a board-certified family medicine physician and the founder of Harborside Healthcare in Mt. Pleasant, South Carolina. She grew up in Charleston, where her father served at the old Naval Shipyard. That connection to the community drives her commitment to caring for the people who shaped her life.
Dr. DeCastro earned her undergraduate degree at the University of South Carolina in Columbia and her medical degree from the University of South Carolina School of Medicine. The United States Air Force awarded her a Health Professions Scholarship, and she served as a Captain and General Medical Officer at Barksdale Air Force Base in Shreveport, Louisiana. She completed her Family Medicine residency at the Medical University of South Carolina and holds board certification from the American Board of Family Medicine. Beyond her practice, she serves as Medical Director at Curana Health and as Supervising Physician for Whole Heart Family Medicine and the Kadima Center for Heart Attack and Stroke Prevention. She currently serves as President of the Charleston County Medical Society. She mentors young physicians, supports community outreach, and fosters collaboration among local healthcare providers. Mt. Pleasant Magazine named her Best Primary Care Physician in 2020, and Healthlinks Magazine recognized her as a Leader in Health and Medicine in its 2026 Women in Health edition.
Education & Training
Undergraduate
University of South Carolina, Columbia
Medical School
University of South Carolina School of Medicine
Residency
Family Medicine, Medical University of South Carolina
Additional Training
Health Professions Scholarship, United States Air Force; served as Captain and General Medical Officer at Barksdale Air Force Base, Shreveport, Louisiana
Certifications
Conditions Treated
Who is Dr. DeCastro right for?
Dr. DeCastro suits patients who want a long-term relationship with a single, accessible physician. Adults managing chronic conditions such as diabetes or cardiovascular disease benefit from her preventive focus. Older adults navigating post-acute or long-term care concerns find her geriatric experience valuable. Patients who value whole-person care covering mental, physical, and spiritual health will feel at home here. New patients require a referral from a provider or an established patient.
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Frequently Asked Questions
Dr. DeCastro treats a broad range of conditions across family medicine. Her clinical focus includes chronic disease management, acute illness, and preventive care. She also has deep experience with post-acute and long-term care, particularly for older adults. Patients dealing with cardiovascular risk, diabetes, or general primary care needs fit well within her practice.
Yes. Dr. DeCastro holds board certification from the American Board of Family Medicine. She completed her residency training in Family Medicine at the Medical University of South Carolina.
Dr. DeCastro earned her medical degree from the University of South Carolina School of Medicine. She completed her Family Medicine residency at the Medical University of South Carolina. Earlier in her career, she served as a Captain and General Medical Officer at Barksdale Air Force Base in Shreveport, Louisiana, following a Health Professions Scholarship with the United States Air Force.
Dr. DeCastro focuses on building long-term, trusting relationships with her patients. She delivers individualized care guided by evidence-based medicine. She considers mental, physical, and spiritual health together when working with patients. She also maintains strong relationships with local specialists to coordinate care when needed.
Yes. Dr. DeCastro has extensive experience with older adult care. She serves as Medical Director at Curana Health, where she cares for post-acute and long-term care patients. That role has deepened her focus on prevention as a tool for managing and reducing chronic disease in aging populations.
Dr. DeCastro currently serves as President of the Charleston County Medical Society. She also serves as Supervising Physician for Whole Heart Family Medicine and the Kadima Center for Heart Attack and Stroke Prevention. She actively mentors young physicians and supports local healthcare collaboration.
Yes. Mt. Pleasant Magazine awarded Dr. DeCastro Best Primary Care Physician and Best Primary Care Practice at Sewee Family Medicine in 2020. Healthlinks Magazine recognized her as a Leader in Health and Medicine in the 2026 Women in Health edition.
Yes. Dr. DeCastro currently accepts new patients through referrals from providers or established patients. Referrals from either source qualify for consideration. Prospective patients should reach out to the practice to begin the process.
Doctor profile last updated April 10, 2026