Dr. George BookMD

Internal Medicine

at George Book, MD — John's Island, SC

About

Dr. George Book is a board-certified internal medicine physician with specialized training in both internal medicine and psychiatry. He earned his Bachelor of Science in Chemistry, Cum Laude, from the University of Florida in 2015 before completing his Doctorate of Medicine at the Medical University of South Carolina in 2020. He then completed a combined Internal Medicine and Psychiatry residency at MUSC, where he served as Chief Resident from 2024 to 2025.

Dr. Book holds the Gold Humanism Honors Society distinction from MUSC and received the James B. Edwards Scholarship throughout medical school. He also completed the Diversity in Addiction Research Training Fellowship at MUSC from 2023 to 2025. His published research spans topics from zinc-induced copper deficiency during COVID-19 to the use of mechanical restraints in academic hospital settings. Clinically, he is passionate about primary care, mental health, women's health, nutrition, sleep, and hypertension. He approaches each patient with the goal of preventing illness, building lasting relationships, and addressing health from every angle, physical, mental, and lifestyle.

Education & Training

Undergraduate

University of Florida, Bachelor of Science, Chemistry, 2015, Cum Laude

Medical School

Medical University of South Carolina, Doctorate of Medicine, 2020

Residency

Internal Medicine & Psychiatry, Medical University of South Carolina, 2021-2025; Chief Resident 2024-2025

Additional Training

Internship: Medical University of South Carolina, 2020-2021; Diversity in Addiction Research Training Fellowship, Medical University of South Carolina, 2023-2025

Certifications

Board Certified in Internal Medicine

Conditions Treated

hypertension
mental health conditions
chronic conditions
type 2 diabetes
high cholesterol
sleep disorders
nutritional concerns

Who is Dr. Book right for?

Dr. Book is a strong fit for adults who want a physician attentive to both physical and mental health. Patients managing chronic conditions like hypertension, high cholesterol, or type 2 diabetes benefit from his proactive approach. He also serves patients with sleep concerns, nutritional questions, and women's health needs. Adults across Charleston, Johns Island, and the Lowcountry who want an engaged, relationship-driven primary care doctor will find a good match in Dr. Book.

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Frequently Asked Questions

Dr. Book treats a broad range of adult conditions, including hypertension, type 2 diabetes, high cholesterol, and sleep disorders. He also addresses mental health conditions, nutritional concerns, and women's health needs. His dual training in internal medicine and psychiatry lets him approach both physical and mental health in a single, integrated relationship.

Yes. Dr. Book holds board certification in internal medicine. He completed his medical education and a combined Internal Medicine and Psychiatry residency at the Medical University of South Carolina, where he also served as Chief Resident in 2024-2025.

Dr. Book believes wellness requires caring for the whole person, body, mind, and lifestyle. He focuses on prevention, early intervention, and building lasting relationships with each patient. He aims to be approachable, attentive, and proactive in helping patients work toward their health goals.

Dr. Book earned his undergraduate degree, Cum Laude, from the University of Florida. He then completed his medical degree, internship, and combined Internal Medicine and Psychiatry residency at the Medical University of South Carolina in Charleston. He was selected as Chief Resident for the 2024-2025 academic year.

Yes. Dr. Book has contributed to peer-reviewed research on several topics. His published work includes a 2022 paper in the American Journal of Medicine on zinc-induced copper deficiency during COVID-19 and a 2024 retrospective analysis of mechanical restraint use at a large academic hospital. He also co-authored a 2018 study in Drug and Alcohol Dependence on N-acetylcysteine and alcohol use.

Yes. Dr. Book trained in both internal medicine and psychiatry at MUSC. He incorporates mental health support into his primary care practice and treats patients dealing with mental health conditions alongside physical concerns. This integrated approach is a core part of how he cares for patients.

Dr. Book serves adult patients across Charleston, Johns Island, and the wider Lowcountry region of South Carolina. His office is located at 1003 Landfall Way, Suite B, in John's Island.

Yes. Dr. Book works directly with MUSC Health and local hospitals to advocate for his patients when they need additional care. Members who require services beyond what the practice provides locally can also access Medical Centers of Excellence through the MDVIP network.

Doctor profile last updated April 4, 2026