About
Elissa Calapai, DO, serves as President and Chief Medical Officer of Cenegenics Boca Raton. She holds a BS in Biology from Fairfield University and earned her Doctor of Osteopathic Medicine from Nova Southeastern University College of Osteopathic Medicine in Fort Lauderdale. Her clinical training included an internship at Miami Heart Institute and a residency in Internal Medicine at the Cleveland Clinic across both Florida and Ohio campuses.
Dr. Calapai practiced office and hospital-based Internal Medicine at North Broward Hospital District from 2001 to 2005, then at Holy Cross Medical Group from 2005 to 2007. She earned her license in Age Management Medicine in 2007 and has dedicated her career to that specialty since. Her long tenure in the field has made her one of the most sought-after age management physicians in southern Florida.
Education & Training
Undergraduate
BS in Biology, Fairfield University, Fairfield, CT
Medical School
Doctor of Osteopathic Medicine, Nova Southeastern University College of Osteopathic Medicine, Fort Lauderdale, FL
Residency
Internal Medicine, Cleveland Clinic (FL and OH)
Additional Training
Internship at Miami Heart Institute; License in Age Management Medicine (2007)
Conditions Treated
Who is Dr. Calapai right for?
Dr. Calapai is a strong fit for adults who want a physician-led approach to aging and long-term health. Patients managing hormonal changes, metabolic concerns, or cardiovascular risk benefit from her preventive focus. Her two-plus decades of internal medicine experience make her well-suited for patients with complex health histories. Adults seeking a structured, science-based path to better healthspan will find her approach direct and thorough.
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Frequently Asked Questions
Dr. Calapai specializes in age management medicine, internal medicine, and preventive medicine. She has focused exclusively on age management since earning her license in the specialty in 2007. Her clinical approach integrates hormonal optimization, functional medicine, and preventive diagnostics.
Dr. Calapai earned her Doctor of Osteopathic Medicine from Nova Southeastern University College of Osteopathic Medicine in Fort Lauderdale. She completed an internship at Miami Heart Institute and finished her Internal Medicine residency at the Cleveland Clinic across its Florida and Ohio campuses.
Dr. Calapai has practiced age management medicine since 2007. Before that specialty focus, she spent several years in office and hospital-based internal medicine at North Broward Hospital District and Holy Cross Medical Group. Her combined experience spans more than two decades of clinical practice in southern Florida.
Dr. Calapai serves as President and Chief Medical Officer of Cenegenics Boca Raton. She also practices at Cenegenics Miami, where she contributes deep expertise in internal medicine and age management to the team.
Dr. Calapai works with adults who want to proactively manage their health and longevity. She is particularly effective with patients dealing with hormonal changes, metabolic health concerns, and cardiovascular risk factors. Her background in internal medicine allows her to manage complex, multi-system health cases.
Dr. Calapai holds a Doctor of Osteopathic Medicine degree. She earned it from Nova Southeastern University College of Osteopathic Medicine in Fort Lauderdale. Osteopathic physicians complete the same medical licensing requirements as MDs and hold full prescribing and hospital privileges.
Doctor profile last updated March 21, 2026