About
Dr. Daphne Stamos Keshishian is a board-certified internist with more than 20 years of clinical experience. She earned her Bachelor of Arts in Spanish with Honors from the University of Pennsylvania in 1988, with a minor in Chemistry. She went on to complete her Doctorate of Medicine at Georgetown University School of Medicine in 1993. She trained at Mount Sinai Medical Center in New York for both her internship and first year of residency in internal medicine. She completed her residency training at Good Samaritan Regional Medical Center in Phoenix, Arizona.
Dr. Keshishian holds certification from the American Board of Internal Medicine and carries the designation of Certified Culinary Medicine Specialist. She brings clinical depth in preventive medicine, women's health, nutrition, and integrative health. She serves as an Associate Clinical Faculty member in the Department of Family Medicine at Georgetown University School of Medicine. She has held leadership roles in the Georgetown Clinical Society, including President from 2012 to 2013 and Executive Board Member in 2020. Castle Connolly named her a Top Doctor from 2019 through 2024, and the Georgetown Clinical Society honored her as Doctor of the Year in 2015. She approaches each patient as a whole person, building relationships that extend beyond the exam room. She conducts appointments in both English and Spanish. Outside the office, her interests include cooking, reading, Pilates, and competitive golf.
Education & Training
Undergraduate
University of Pennsylvania, Bachelor of Arts, Spanish with Honors, 1988; Minor in Chemistry
Medical School
Georgetown University School of Medicine, Doctorate of Medicine, 1993
Residency
Internal Medicine, Mount Sinai Medical Center, New York, NY (1994-1995); Internal Medicine, Good Samaritan Regional Medical Center, Phoenix, AZ (1995-1996)
Additional Training
Internship: Internal Medicine, Mount Sinai Medical Center, New York, NY (1993-1994)
Certifications
Languages
English, Spanish
Conditions Treated
Who is Dr. Keshishian right for?
Dr. Keshishian is a strong fit for adults seeking a physician who treats the whole person, not isolated symptoms. Patients managing chronic conditions, cardiovascular risk, or women's health concerns benefit from her preventive and integrative approach. She works particularly well with patients who want guidance on nutrition and lifestyle alongside clinical care. Spanish-speaking patients find her practice especially accessible. Adults who value a long-term, relationship-driven physician relationship tend to thrive under her care.
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Frequently Asked Questions
Dr. Keshishian treats a broad range of adult conditions, with particular focus on chronic disease management, women's health, and nutrition-related conditions. Her clinical interests also include preventive medicine and integrative health. She approaches care by looking at the whole patient rather than individual organ systems.
Yes, Dr. Keshishian holds board certification from the American Board of Internal Medicine. She also carries certification as a Culinary Medicine Specialist, which she applies to her nutrition-focused patient guidance.
Dr. Keshishian earned her medical degree from Georgetown University School of Medicine in 1993. She completed her internship and first residency year at Mount Sinai Medical Center in New York. She finished her residency training at Good Samaritan Regional Medical Center in Phoenix, Arizona.
Yes. Dr. Keshishian maintains affiliations at Shady Grove Medical Center in Rockville, Maryland, and Suburban Hospital in Bethesda, Maryland. She personally visits her patients at both facilities when they require hospital care.
Nutrition is a core part of how Dr. Keshishian supports patient health. As a Certified Culinary Medicine Specialist, she shares practical cooking tips and dietary guidance during appointments. She also incorporates exercise recommendations, including Pilates and Yoga, to support flexibility, sleep, and core strength.
Yes. Dr. Keshishian speaks fluent English and Spanish. She conducts appointments in both languages, making her practice accessible to Spanish-speaking patients in the Bethesda area.
Castle Connolly named Dr. Keshishian a Top Doctor every year from 2019 through 2024. The Georgetown Clinical Society honored her as Doctor of the Year in 2015 and also awarded her the St. Ignatius of Loyola Award that same year. Washingtonian and Bethesda Magazine have each recognized her as a Top Doctor as well.
Dr. Keshishian serves as Associate Clinical Faculty in the Department of Family Medicine at Georgetown University School of Medicine. She has held multiple leadership roles in the Georgetown Clinical Society, including Secretary, Vice President, President, and Executive Board Member. She also serves on the Peer Review Committee in the Department of Internal Medicine at Shady Grove Medical Center.
Doctor profile last updated April 11, 2026