About
Dr. Daniel Smith is a board-certified internist practicing in Greenville, South Carolina. He earned his Bachelor of Science in Biology, Magna Cum Laude, from the University of South Carolina in 2004. He then completed his Doctorate of Medicine at the University of South Carolina School of Medicine in 2008. His internship took place at Prisma Health Greenville Memorial Hospital, followed by an Internal Medicine residency at Greenville Health System/Prisma. He served as Chief Resident during his final year, from 2010 to 2011. He holds certification from the American Board of Internal Medicine and maintains affiliations with Prisma Health - Greer and Greenville Hospitals. He is also a member of the South Carolina Medical Association.
Dr. Smith takes a humanistic approach to patient care. He treats a wide range of conditions, including diabetes, hypertension, obesity, chronic kidney disease, asthma, COPD, and irritable bowel syndrome. He places particular emphasis on nutrition, physical activity, and preventive care. He believes good medicine starts with listening and encourages each patient to set their own health goals. Patients consistently describe him as personable, attentive, and thorough. Outside the office, Dr. Smith enjoys time with family and friends, visits to the beach, mountains, and lake, day drives, and reading.
Education & Training
Undergraduate
University of South Carolina, Bachelor of Science, Biology, Magna Cum Laude, 2004
Medical School
University of South Carolina School of Medicine, Doctorate of Medicine, 2008
Residency
Internal Medicine, Greenville Health System/Prisma, Greenville, SC, 2009-2011; Chief Resident 2010-2011
Additional Training
Internship: Prisma Health Greenville Memorial Hospital, Greenville, SC, 2008-2009
Certifications
Conditions Treated
Who is Dr. Smith right for?
Dr. Smith is a strong fit for adults seeking a relationship-driven approach to internal medicine. Patients managing chronic conditions like diabetes, hypertension, obesity, or chronic kidney disease benefit from his focused, ongoing care. He works well with patients who want an active role in setting their own health goals. Those who value in-person, hands-on care and direct access to their physician will find his practice a natural fit.
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Frequently Asked Questions
Dr. Smith treats a broad range of adult conditions. His clinical focus includes diabetes, hypertension, obesity, chronic kidney disease, asthma, COPD, and irritable bowel syndrome. He also provides preventive care, nutrition counseling, and physical activity guidance.
Yes, Dr. Smith holds board certification from the American Board of Internal Medicine. He completed his residency at Greenville Health System/Prisma, where he served as Chief Resident from 2010 to 2011.
Dr. Smith earned his medical degree from the University of South Carolina School of Medicine in 2008. He completed his internship at Prisma Health Greenville Memorial Hospital and his Internal Medicine residency at Greenville Health System/Prisma in Greenville, SC.
Dr. Smith takes a humanistic approach to medicine. He encourages patients to define their own health goals and works alongside them to achieve those goals. He prioritizes in-person, hands-on care and emphasizes healthy living, nutrition, and physical activity.
Yes. Dr. Smith is reachable by phone after hours and on weekends. Members can contact him directly without going through a general voicemail system.
Yes, Dr. Smith offers telehealth and virtual visit options. He views them as a useful complement to in-person care, not a replacement for hands-on appointments when those are needed.
Dr. Smith holds affiliations with Prisma Health - Greer and Greenville Hospitals. Members who need hospital-level care benefit from his direct connection to those facilities.
Yes. Dr. Smith sees patients from Greenville and the surrounding areas, including Greer, Taylors, Landrum, Easley, and Spartanburg.
Members always see Dr. Smith directly. The practice does not route patients to a nurse practitioner or physician assistant in place of the doctor.
Doctor profile last updated April 4, 2026
