Dr. Curtis Takemoto-GentileMD
Family Medicine
at Kaimana Hila Direct Primary Care LLC and Optimal HealthCare Direct LLC — Honolulu, HI
About
Dr. Curtis Takemoto-Gentile began his medical career as an Associate Professor at the University of Hawaiʻi, John A. Burns School of Medicine. He transitioned into private practice more than 35 years ago. Today he cares for patients of all ages, from newborns through centenarians, with a functional medicine perspective. Dr. Takemoto-Gentile focuses on how the body functions as a whole. He identifies areas of dysfunction and works to restore balance using natural therapies, nutritional support, and prescription medications when appropriate. Diet, vitamins, and hormone balance form the foundation of his approach to sustaining long-term physical and mental health. Many of his patients maintain excellent health without relying on long-term prescription medications. He integrates allopathic and naturopathic medicine, and he brings more than 35 combined years of experience in evidence-based bioidentical hormone therapy alongside Dr. Krishanna.
Education & Training
Additional Training
Associate Professor, University of Hawaiʻi, John A. Burns School of Medicine (academic medicine career prior to private practice)
Conditions Treated
Who is Dr. Takemoto-Gentile right for?
Dr. Takemoto-Gentile is an excellent fit for patients who want a root-cause approach to their health. Adults of any age managing chronic conditions such as high blood pressure, diabetes, high cholesterol, or thyroid disorders benefit from his functional medicine lens. Patients interested in reducing long-term reliance on prescription medications will find his nutritional and naturopathic tools especially relevant. He also serves patients seeking hormone optimization, from men and women navigating hormone deficiency to those pursuing proactive longevity strategies.
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Frequently Asked Questions
Dr. Curtis Takemoto-Gentile treats thyroid disorders, high blood pressure, diabetes, fatigue, allergies, food sensitivities, high cholesterol, hormone imbalance, and hormone deficiency. He also manages preventive care and chronic disease for patients across all age groups, from newborns to patients over 100 years old.
Dr. Curtis Takemoto-Gentile approaches medicine from a functional perspective. He evaluates how the body works as a whole, identifies areas of dysfunction, and uses natural therapies, nutritional support, and prescription medications when appropriate. He tailors every plan to the patient's age and life stage.
Dr. Curtis Takemoto-Gentile has practiced privately for more than 35 years. He began his career in academic medicine as an Associate Professor at the University of Hawaiʻi, John A. Burns School of Medicine before transitioning to private practice.
Yes. Dr. Curtis Takemoto-Gentile provides hormone replacement therapy for both men and women. He and Dr. Krishanna together bring more than 35 combined years of experience in evidence-based bioidentical hormone therapy. The practice's Ke Ala Hormone Program supports structured hormone care for eligible patients.
Many of Dr. Curtis Takemoto-Gentile's patients do maintain excellent health without long-term prescription medications. He focuses on diet, vitamins, hormone balance, and natural therapies to address root causes. Prescription medications remain an option when clinically appropriate, but they are not his default starting point.
Yes. Dr. Curtis Takemoto-Gentile provides care across the full age spectrum, from newborns through patients over 100 years old. Note that the DPC membership for patients under 14 has specific enrollment requirements; contact the practice for details.
Dr. Curtis Takemoto-Gentile draws on both conventional medicine and evidence-based natural therapies. He incorporates nutritional support, natural supplements, and lifestyle interventions alongside prescription treatments when needed. The practice has refined this integrative approach over more than 25 years.
Doctor profile last updated April 11, 2026